Download e-book for iPad: Axonal Branching and Recovery of Coordinated Muscle Activity by D.N. Angelov, O. Guntinas-Lichius, K. Wewetzer, W.F. Neiss,

By D.N. Angelov, O. Guntinas-Lichius, K. Wewetzer, W.F. Neiss, M. Streppel

ISBN-10: 3540256547

ISBN-13: 9783540256540

ISBN-10: 3540299319

ISBN-13: 9783540299318

Facial nerve surgical procedure unavoidably results in partial pareses, abnormally linked routine and pathologically altered reflexes. the cause of this "post-paralytic syndrome" is the misdirected reinnervation of pursuits, which is composed of 2 significant parts. First, as a result of malfunctioning axonal counsel, a muscle will get reinnervated by way of a "foreign" axon, that has been misrouted alongside a "wrong" fascicle. moment, the supernumerary collateral branches rising from all transected axons at the same time innervate adverse muscle tissues and reason serious impairment in their coordinated job. because it is not often attainable to persuade the 1st significant part and enhance the assistance of numerous millions axons, the authors targeting the second one significant part and attempted to lessen the collateral axonal branching.

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Additional resources for Axonal Branching and Recovery of Coordinated Muscle Activity after Transsection of the Facial Nerve in Adult Rats (Advances in Anatomy, Embryology and Cell Biology)

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Contralateral Intact Facial Nucleus All retrogradely labeled neurons (FG, FB, and FG+FB) were localized exclusively in the lateral facial subnucleus (Fig. 11A–C). Thus, on the side of the brainstem contralateral to BBA, there were no detectable differences among all three types of operations either in location or in numbers of FG-, FB-, and FG+FB-labeled neurons (one way ANOVA; no significance). Buccal–Buccal Anastomosis Neuronal labeling 28 days after BBA showed that all FG-labeled neurons were located in the lateral facial subnucleus (Fig.

3 Schematic drawing of the extratemporal rat facial nerve indicating the site of intramuscular injection of Fluoro-Gold and Fast Blue. (Adapted from Dörfl 1985, Semba and Egger 1986; reprinted from Popratiloff et al. 3 Effect of Altered Trigeminal Input to Axotomized Facial Perikarya on the Accuracy of Reinnervation Animals Group C consisted of 41 rats distributed in four subgroups (C1 –C4 ). These rats were used for counts after retrograde labeling of facial motoneurons by intramuscular application of tracers.

Reprinted from Popratiloff et al. 2001) any kind of surgery. ” The key movements of this motor activity are the protraction (Fig. 5A) and retraction (Fig. 5B) of the vibrissal hairs by the piloerector muscles. All muscles are innervated by the buccal branch of the facial nerve (Dörfl 1985). Videotaping Only two large vibrissae of the caudal “C-row” on each side of the face were used for biometric analysis. Under light ether anesthesia, all other vibrissae were clipped with small fine scissors. Thereafter the animals were inserted into a rodent restrainer (Hugo Sachs Electronik–Harvard Apparatus GmbH, March-Hugstetten, Germany) and left in peace for approximately 30 min to calm down.

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Axonal Branching and Recovery of Coordinated Muscle Activity after Transsection of the Facial Nerve in Adult Rats (Advances in Anatomy, Embryology and Cell Biology) by D.N. Angelov, O. Guntinas-Lichius, K. Wewetzer, W.F. Neiss, M. Streppel


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