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By Jeffrey M. Drazen (auth.), Zeliha Yazici, Giancarlo C. Folco, Jeffrey M. Drazen, Santosh Nigam, Takao Shimizu (eds.)

ISBN-10: 1461348315

ISBN-13: 9781461348313

This quantity, the lawsuits of the twelfth overseas convention on Advances in Prostaglandin, Leukotriene and different Bioactive Lipid learn: uncomplicated technology and medical functions, held August 25-29, 2002, in Istanbul, Turkey, discusses advances in bioactive lipid study with designated consciousness to melanoma, cardiovascular illnesses, gastrointestinal illnesses and respiration illnesses. particular subject matters coated contain the function of leukotrienes and lipoxins in irritation, the cytochrome P450 pathway, the genetics and genomics of bioactive lipids, lipid peroxidation, apoptosis, angiogenesis, isoprostanes, receptors and inhibitors, cyclooxygenase and lipoxygenase pathways and inhibitors, prostaglandin synthases and receptor signaling, phospholipases and inhibitors.

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Extra resources for Advances in Prostaglandin, Leukotriene, and other Bioactive Lipid Research: Basic Science and Clinical Applications

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Glucocorticoids, teophyllin, 132 agonists and leukotriene modifierspharmacogenetic associations have been described only for 132 agonists and leukotriene modifiers [I] . Studies on 132 agonists have shown that polymorphisms at the 132 receptor may influence airway responses to regular inhaled 13 agonist treatment and the acute response to 13 agonists [2,3]. Pharmacogenetic studies of leukotriene modifiers, on the other hand, have investigated the effect of polymorphisms of two enzymes that participate in leukotriene biosynthesis- Leukotriene (LT) C4 synthase and 5lipoygenase (ALOX-5)- on the response to agents that inhibit leukotriene biosynthesis or block their effect at the receptor level.

4. 5. 6. 7. 8. Palmer LJ, Silverman ES, Weiss ST, Drazen JM. Pharmacogenetics of asthma. Am J Respir Crit Care Med 2002; 165:861-866. Israel E, Drazen JM, Liggett SB, Boushey HA, Cherniack RM, Chin chilli VM, Cooper DM, Fahy N, Fish JE, Ford JG, Kraft M, Kunselman S, Lazarus SC, Lemanske RF, Marrin RJ, McLean DE, Peters SP, Silverman EK, Sorkness CA, Szefler SJ, Weiss ST, Yandava CN. The effect of polymorphisms of the beta(2)adrenergic receptor on the response to regular use of albuterol in asthma.

Effects of intravenous administration of slow-reacting substance of anaphylaxis, histamine, bradykinin , and prostaglandin F2alpha on pulmonary mechanics in the guinea pig. J Clin Invest 1974; 53: 1679-1685. Brocklehurst WE. The release of histamine and the formation of a slow-reacting substance (SRS-A) during anaphylactic shock. J Physiol (Lond) 1960; 151:416-435. Murphy RC, Hammarstrom S, Samuelsson B. Leukotriene C: a slow-reacting substance from murine mastocytoma cells. Proc Natl Acad Sci USA 1979; 76:42754279.

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Advances in Prostaglandin, Leukotriene, and other Bioactive Lipid Research: Basic Science and Clinical Applications by Jeffrey M. Drazen (auth.), Zeliha Yazici, Giancarlo C. Folco, Jeffrey M. Drazen, Santosh Nigam, Takao Shimizu (eds.)


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